YEATS4-CPSF6 Fusion FISH Probe
The YEATS4-CPSF6 Fusion FISH Probe is used to confirm a fusion of the YEATS4 and CPSF6 genes. The fusion of the YEATS4 and CPSF6 genes has been associated with Rectum Adenocarcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| YEATS4-CPSF6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-RERE | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-REOR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-REGO | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-REGR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-REAQ | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-ORRE | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-OROR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-ORGO | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-ORAQ | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GORE | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GOOR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GOGO | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GOGR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GOAQ | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GRRE | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GROR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GRGO | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GRGR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-GRAQ | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-AQRE | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-AQOR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-AQGO | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-AQGR | 20 (40 μL) | 200 μL |
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| YEATS4-CPSF6-20-AQAQ | 20 (40 μL) | 200 μL |
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YEATS4 Gene Summary
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Name: YEATS Domain Containing 4
Chromosome: CHR12: 69753531 -69784576
Locus: 12q15
CPSF6 Gene Summary
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
Gene Name: Cleavage And Polyadenylation Specific Factor 6
Chromosome: CHR12: 69633316 -69668138
Locus: 12q15
Gene Diseases
The YEATS4 CPSF6 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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