YAP1-RNF130 Fusion FISH Probe
The YAP1-RNF130 Fusion FISH Probe is used to confirm a fusion of the YAP1 and RNF130 genes. The fusion of the YAP1 and RNF130 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| YAP1-RNF130-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-RERE | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-REOR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-REGO | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-REGR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-REAQ | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-ORRE | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-OROR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-ORGO | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-ORAQ | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GORE | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GOOR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GOGO | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GOGR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GOAQ | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GRRE | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GROR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GRGO | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GRGR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-GRAQ | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-AQRE | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-AQOR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-AQGO | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-AQGR | 20 (40 μL) | 200 μL |
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| YAP1-RNF130-20-AQAQ | 20 (40 μL) | 200 μL |
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YAP1 Gene Summary
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Gene Name: Yes Associated Protein 1
Chromosome: CHR11: 101981191 -102104154
Locus: 11q22.1
RNF130 Gene Summary
The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Ring Finger Protein 130
Chromosome: CHR5: 179382473 -179499109
Locus: 5q35.3
Gene Diseases
The YAP1 RNF130 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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