XYLT1-QPRT Fusion FISH Probe
The XYLT1-QPRT Fusion FISH Probe is used to confirm a fusion of the XYLT1 and QPRT genes. The fusion of the XYLT1 and QPRT genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| XYLT1-QPRT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-RERE | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-REOR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-REGO | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-REGR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-REAQ | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-ORRE | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-OROR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-ORGO | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-ORAQ | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GORE | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GOOR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GOGO | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GOGR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GOAQ | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GRRE | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GROR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GRGO | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GRGR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-GRAQ | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-AQRE | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-AQOR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-AQGO | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-AQGR | 20 (40 μL) | 200 μL |
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| XYLT1-QPRT-20-AQAQ | 20 (40 μL) | 200 μL |
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QPRT Gene Summary
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Quinolinate Phosphoribosyltransferase
Chromosome: CHR16: 29690440 -29709314
Locus: 16p11.2
XYLT1 Gene Summary
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]
Gene Name: Xylosyltransferase 1
Chromosome: CHR16: 17196180 -17564738
Locus: 16p12.3
Gene Diseases
The XYLT1 QPRT Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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