XYLT1-HS3ST4 Fusion FISH Probe
The XYLT1-HS3ST4 Fusion FISH Probe is used to confirm a fusion of the XYLT1 and HS3ST4 genes. The fusion of the XYLT1 and HS3ST4 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| XYLT1-HS3ST4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-RERE | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-REOR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-REGO | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-REGR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-REAQ | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-ORRE | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-OROR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-ORGO | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-ORAQ | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GORE | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GOOR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GOGO | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GOGR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GOAQ | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GRRE | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GROR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GRGO | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GRGR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-GRAQ | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-AQRE | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-AQOR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-AQGO | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-AQGR | 20 (40 μL) | 200 μL |
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| XYLT1-HS3ST4-20-AQAQ | 20 (40 μL) | 200 μL |
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HS3ST4 Gene Summary
This gene encodes the enzyme heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4. This enzyme generates 3-O-sulfated glucosaminyl residues in heparan sulfate. Cell surface heparan sulfate is used as a receptor by herpes simplex virus type 1 (HSV-1), and expression of this gene is thought to play a role in HSV-1 pathogenesis. [provided by RefSeq, Jul 2008]
Gene Name: Heparan Sulfate-glucosamine 3-sulfotransferase 4
Chromosome: CHR16: 25703346 -26149009
Locus: 16p12.1
XYLT1 Gene Summary
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]
Gene Name: Xylosyltransferase 1
Chromosome: CHR16: 17196180 -17564738
Locus: 16p12.3
Gene Diseases
The XYLT1 HS3ST4 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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