XYLT1-GALNT6 Fusion FISH Probe
The XYLT1-GALNT6 Fusion FISH Probe is used to confirm a fusion of the XYLT1 and GALNT6 genes. The fusion of the XYLT1 and GALNT6 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| XYLT1-GALNT6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-RERE | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-REOR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-REGO | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-REGR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-REAQ | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-ORRE | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-OROR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-ORGO | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GORE | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GOOR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GOGO | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GOGR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GRRE | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GROR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GRGO | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GRGR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-AQRE | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-AQOR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-AQGO | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-AQGR | 20 (40 μL) | 200 μL |
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| XYLT1-GALNT6-20-AQAQ | 20 (40 μL) | 200 μL |
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GALNT6 Gene Summary
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008]
Gene Name: Polypeptide N-acetylgalactosaminyltransferase 6
Chromosome: CHR12: 51745832 -51785200
Locus: 12q13.13
XYLT1 Gene Summary
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]
Gene Name: Xylosyltransferase 1
Chromosome: CHR16: 17196180 -17564738
Locus: 16p12.3
Gene Diseases
The XYLT1 GALNT6 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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