XRN1-SMYD3 Fusion FISH Probe
The XRN1-SMYD3 Fusion FISH Probe is used to confirm a fusion of the XRN1 and SMYD3 genes. The fusion of the XRN1 and SMYD3 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| XRN1-SMYD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-RERE | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-REOR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-REGO | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-REGR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-REAQ | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-ORRE | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-OROR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-ORGO | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GORE | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GOOR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GOGO | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GOGR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GRRE | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GROR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GRGO | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GRGR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-AQRE | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-AQOR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-AQGO | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-AQGR | 20 (40 μL) | 200 μL |
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| XRN1-SMYD3-20-AQAQ | 20 (40 μL) | 200 μL |
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XRN1 Gene Summary
This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: 5'-3' Exoribonuclease 1
Chromosome: CHR3: 142025448 -142166853
Locus: 3q23
SMYD3 Gene Summary
This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: SET And MYND Domain Containing 3
Chromosome: CHR1: 245912641 -246670644
Locus: 1q44
Gene Diseases
The XRN1 SMYD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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