XRCC5-ACADL Fusion FISH Probe
The XRCC5-ACADL Fusion FISH Probe is used to confirm a fusion of the XRCC5 and ACADL genes. The fusion of the XRCC5 and ACADL genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| XRCC5-ACADL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-RERE | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-REOR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-REGO | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-REGR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-REAQ | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-ORRE | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-OROR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-ORGO | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-ORAQ | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GORE | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GOOR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GOGO | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GOGR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GOAQ | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GRRE | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GROR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GRGO | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GRGR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-GRAQ | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-AQRE | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-AQOR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-AQGO | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-AQGR | 20 (40 μL) | 200 μL |
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| XRCC5-ACADL-20-AQAQ | 20 (40 μL) | 200 μL |
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ACADL Gene Summary
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008]
Gene Name: Acyl-CoA Dehydrogenase Long Chain
Chromosome: CHR2: 211052715 -211090215
Locus: 2q34
XRCC5 Gene Summary
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Gene Name: X-ray Repair Cross Complementing 5
Chromosome: CHR2: 216974019 -217071016
Locus: 2q35
Gene Diseases
The XRCC5 ACADL Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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