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XPR1-NCF2 Fusion FISH Probe

The XPR1-NCF2 Fusion FISH Probe is used to confirm a fusion of the XPR1 and NCF2 genes. The fusion of the XPR1 and NCF2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
XPR1-NCF2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
XPR1-NCF2-20-RERE 20 (40 μL) 200 μL
XPR1-NCF2-20-REOR 20 (40 μL) 200 μL
XPR1-NCF2-20-REGO 20 (40 μL) 200 μL
XPR1-NCF2-20-REGR 20 (40 μL) 200 μL
XPR1-NCF2-20-REAQ 20 (40 μL) 200 μL
XPR1-NCF2-20-ORRE 20 (40 μL) 200 μL
XPR1-NCF2-20-OROR 20 (40 μL) 200 μL
XPR1-NCF2-20-ORGO 20 (40 μL) 200 μL
XPR1-NCF2-20-ORAQ 20 (40 μL) 200 μL
XPR1-NCF2-20-GORE 20 (40 μL) 200 μL
XPR1-NCF2-20-GOOR 20 (40 μL) 200 μL
XPR1-NCF2-20-GOGO 20 (40 μL) 200 μL
XPR1-NCF2-20-GOGR 20 (40 μL) 200 μL
XPR1-NCF2-20-GOAQ 20 (40 μL) 200 μL
XPR1-NCF2-20-GRRE 20 (40 μL) 200 μL
XPR1-NCF2-20-GROR 20 (40 μL) 200 μL
XPR1-NCF2-20-GRGO 20 (40 μL) 200 μL
XPR1-NCF2-20-GRGR 20 (40 μL) 200 μL
XPR1-NCF2-20-GRAQ 20 (40 μL) 200 μL
XPR1-NCF2-20-AQRE 20 (40 μL) 200 μL
XPR1-NCF2-20-AQOR 20 (40 μL) 200 μL
XPR1-NCF2-20-AQGO 20 (40 μL) 200 μL
XPR1-NCF2-20-AQGR 20 (40 μL) 200 μL
XPR1-NCF2-20-AQAQ 20 (40 μL) 200 μL

NCF2 Gene Summary

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

Gene Name: Neutrophil Cytosolic Factor 2

Chromosome: CHR1: 183524696 -183560056

Locus: 1q25.3

XPR1 Gene Summary

The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6. [provided by RefSeq, Jun 2016]

Gene Name: Xenotropic And Polytropic Retrovirus Receptor 1

Chromosome: CHR1: 180601145 -180859415

Locus: 1q25.3

Gene Diseases

The XPR1 NCF2 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.