XPR1-NCF2 Fusion FISH Probe
The XPR1-NCF2 Fusion FISH Probe is used to confirm a fusion of the XPR1 and NCF2 genes. The fusion of the XPR1 and NCF2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| XPR1-NCF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-RERE | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-REOR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-REGO | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-REGR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-REAQ | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-ORRE | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-OROR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-ORGO | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GORE | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GOOR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GOGO | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GOGR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GRRE | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GROR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GRGO | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GRGR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-AQRE | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-AQOR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-AQGO | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-AQGR | 20 (40 μL) | 200 μL |
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| XPR1-NCF2-20-AQAQ | 20 (40 μL) | 200 μL |
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NCF2 Gene Summary
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
Gene Name: Neutrophil Cytosolic Factor 2
Chromosome: CHR1: 183524696 -183560056
Locus: 1q25.3
XPR1 Gene Summary
The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6. [provided by RefSeq, Jun 2016]
Gene Name: Xenotropic And Polytropic Retrovirus Receptor 1
Chromosome: CHR1: 180601145 -180859415
Locus: 1q25.3
Gene Diseases
The XPR1 NCF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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