XPO4-SSRP1 Fusion FISH Probe
The XPO4-SSRP1 Fusion FISH Probe is used to confirm a fusion of the XPO4 and SSRP1 genes. The fusion of the XPO4 and SSRP1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| XPO4-SSRP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-RERE | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-REOR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-REGO | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-REGR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-REAQ | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-ORRE | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-OROR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-ORGO | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GORE | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GOOR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GOGO | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GOGR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GRRE | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GROR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GRGO | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GRGR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-AQRE | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-AQOR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-AQGO | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-AQGR | 20 (40 μL) | 200 μL |
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| XPO4-SSRP1-20-AQAQ | 20 (40 μL) | 200 μL |
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SSRP1 Gene Summary
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008]
Gene Name: Structure Specific Recognition Protein 1
Chromosome: CHR11: 57093458 -57103351
Locus: 11q12.1
XPO4 Gene Summary
XPO4 belongs to a large family of karyopherins (see MIM 602738) that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments (Lipowsky et al., 2000 [PubMed 10944119]).[supplied by OMIM, Mar 2009]
Gene Name: Exportin 4
Chromosome: CHR13: 21351467 -21476913
Locus: 13q12.11
Gene Diseases
The XPO4 SSRP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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