WWP2-TMCO7 Fusion FISH Probe
The WWP2-TMCO7 Fusion FISH Probe is used to confirm a fusion of the WWP2 and TMCO7 genes. The fusion of the WWP2 and TMCO7 genes has been associated with Ovarian Serous Cystadenocarcinoma, Lung Squamous Cell Carcinoma, and Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WWP2-TMCO7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-RERE | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-REOR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-REGO | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-REGR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-REAQ | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-ORRE | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-OROR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-ORGO | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-ORAQ | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GORE | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GOOR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GOGO | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GOGR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GOAQ | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GRRE | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GROR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GRGO | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GRGR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-GRAQ | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-AQRE | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-AQOR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-AQGO | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-AQGR | 20 (40 μL) | 200 μL |
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| WWP2-TMCO7-20-AQAQ | 20 (40 μL) | 200 μL |
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WWP2 Gene Summary
This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10. [provided by RefSeq, Jul 2012]
Gene Name: WW Domain Containing E3 Ubiquitin Protein Ligase 2
Chromosome: CHR16: 69796273 -69975643
Locus: 16q22.1
Gene Diseases
The WWP2 TMCO7 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Lung Squamous Cell Carcinoma |
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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