WWP2-NFAT5 Fusion FISH Probe
The WWP2-NFAT5 Fusion FISH Probe is used to confirm a fusion of the WWP2 and NFAT5 genes. The fusion of the WWP2 and NFAT5 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WWP2-NFAT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-RERE | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-REOR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-REGO | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-REGR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-REAQ | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-ORRE | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-OROR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-ORGO | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GORE | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GOOR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GOGO | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GOGR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GRRE | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GROR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GRGO | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GRGR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-AQRE | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-AQOR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-AQGO | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-AQGR | 20 (40 μL) | 200 μL |
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| WWP2-NFAT5-20-AQAQ | 20 (40 μL) | 200 μL |
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NFAT5 Gene Summary
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Factor Of Activated T-cells 5
Chromosome: CHR16: 69599868 -69738569
Locus: 16q22.1
WWP2 Gene Summary
This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10. [provided by RefSeq, Jul 2012]
Gene Name: WW Domain Containing E3 Ubiquitin Protein Ligase 2
Chromosome: CHR16: 69796273 -69975643
Locus: 16q22.1
Gene Diseases
The WWP2 NFAT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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