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WWP2-CYB5B Fusion FISH Probe

The WWP2-CYB5B Fusion FISH Probe is used to confirm a fusion of the WWP2 and CYB5B genes. The fusion of the WWP2 and CYB5B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
WWP2-CYB5B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
WWP2-CYB5B-20-RERE 20 (40 μL) 200 μL
WWP2-CYB5B-20-REOR 20 (40 μL) 200 μL
WWP2-CYB5B-20-REGO 20 (40 μL) 200 μL
WWP2-CYB5B-20-REGR 20 (40 μL) 200 μL
WWP2-CYB5B-20-REAQ 20 (40 μL) 200 μL
WWP2-CYB5B-20-ORRE 20 (40 μL) 200 μL
WWP2-CYB5B-20-OROR 20 (40 μL) 200 μL
WWP2-CYB5B-20-ORGO 20 (40 μL) 200 μL
WWP2-CYB5B-20-ORAQ 20 (40 μL) 200 μL
WWP2-CYB5B-20-GORE 20 (40 μL) 200 μL
WWP2-CYB5B-20-GOOR 20 (40 μL) 200 μL
WWP2-CYB5B-20-GOGO 20 (40 μL) 200 μL
WWP2-CYB5B-20-GOGR 20 (40 μL) 200 μL
WWP2-CYB5B-20-GOAQ 20 (40 μL) 200 μL
WWP2-CYB5B-20-GRRE 20 (40 μL) 200 μL
WWP2-CYB5B-20-GROR 20 (40 μL) 200 μL
WWP2-CYB5B-20-GRGO 20 (40 μL) 200 μL
WWP2-CYB5B-20-GRGR 20 (40 μL) 200 μL
WWP2-CYB5B-20-GRAQ 20 (40 μL) 200 μL
WWP2-CYB5B-20-AQRE 20 (40 μL) 200 μL
WWP2-CYB5B-20-AQOR 20 (40 μL) 200 μL
WWP2-CYB5B-20-AQGO 20 (40 μL) 200 μL
WWP2-CYB5B-20-AQGR 20 (40 μL) 200 μL
WWP2-CYB5B-20-AQAQ 20 (40 μL) 200 μL

WWP2 Gene Summary

This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10. [provided by RefSeq, Jul 2012]

Gene Name: WW Domain Containing E3 Ubiquitin Protein Ligase 2

Chromosome: CHR16: 69796273 -69975643

Locus: 16q22.1

CYB5B Gene Summary

The Cytochrome B5 Type B (CYB5B) gene is located on chr16 :69458497-69500167 at 16q22.1.

Gene Name: Cytochrome B5 Type B

Chromosome: CHR16: 69458497 -69500167

Locus: 16q22.1

Gene Diseases

The WWP2 CYB5B Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.