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WWP1-ESRP1 Fusion FISH Probe

The WWP1-ESRP1 Fusion FISH Probe is used to confirm a fusion of the WWP1 and ESRP1 genes. The fusion of the WWP1 and ESRP1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
WWP1-ESRP1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
WWP1-ESRP1-20-RERE 20 (40 μL) 200 μL
WWP1-ESRP1-20-REOR 20 (40 μL) 200 μL
WWP1-ESRP1-20-REGO 20 (40 μL) 200 μL
WWP1-ESRP1-20-REGR 20 (40 μL) 200 μL
WWP1-ESRP1-20-REAQ 20 (40 μL) 200 μL
WWP1-ESRP1-20-ORRE 20 (40 μL) 200 μL
WWP1-ESRP1-20-OROR 20 (40 μL) 200 μL
WWP1-ESRP1-20-ORGO 20 (40 μL) 200 μL
WWP1-ESRP1-20-ORAQ 20 (40 μL) 200 μL
WWP1-ESRP1-20-GORE 20 (40 μL) 200 μL
WWP1-ESRP1-20-GOOR 20 (40 μL) 200 μL
WWP1-ESRP1-20-GOGO 20 (40 μL) 200 μL
WWP1-ESRP1-20-GOGR 20 (40 μL) 200 μL
WWP1-ESRP1-20-GOAQ 20 (40 μL) 200 μL
WWP1-ESRP1-20-GRRE 20 (40 μL) 200 μL
WWP1-ESRP1-20-GROR 20 (40 μL) 200 μL
WWP1-ESRP1-20-GRGO 20 (40 μL) 200 μL
WWP1-ESRP1-20-GRGR 20 (40 μL) 200 μL
WWP1-ESRP1-20-GRAQ 20 (40 μL) 200 μL
WWP1-ESRP1-20-AQRE 20 (40 μL) 200 μL
WWP1-ESRP1-20-AQOR 20 (40 μL) 200 μL
WWP1-ESRP1-20-AQGO 20 (40 μL) 200 μL
WWP1-ESRP1-20-AQGR 20 (40 μL) 200 μL
WWP1-ESRP1-20-AQAQ 20 (40 μL) 200 μL

WWP1 Gene Summary

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008]

Gene Name: WW Domain Containing E3 Ubiquitin Protein Ligase 1

Chromosome: CHR8: 87354993 -87480178

Locus: 8q21.3

ESRP1 Gene Summary

ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009]

Gene Name: Epithelial Splicing Regulatory Protein 1

Chromosome: CHR8: 95653363 -95719694

Locus: 8q22.1

Gene Diseases

The WWP1 ESRP1 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.