WWOX-VAT1L Fusion FISH Probe
The WWOX-VAT1L Fusion FISH Probe is used to confirm a fusion of the WWOX and VAT1L genes. The fusion of the WWOX and VAT1L genes has been associated with Colon Adenocarcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WWOX-VAT1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-RERE | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-REOR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-REGO | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-REGR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-REAQ | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-ORRE | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-OROR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-ORGO | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GORE | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GOOR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GOGO | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GOGR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GRRE | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GROR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GRGO | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GRGR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-AQRE | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-AQOR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-AQGO | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-AQGR | 20 (40 μL) | 200 μL |
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| WWOX-VAT1L-20-AQAQ | 20 (40 μL) | 200 μL |
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WWOX Gene Summary
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: WW Domain Containing Oxidoreductase
Chromosome: CHR16: 78133326 -79246564
Locus: 16q23.1-q23.2
VAT1L Gene Summary
The Vesicle Amine Transport 1 Like (VAT1L) gene is located on chr16 :77822482-78014001 at 16q23.1.
Gene Name: Vesicle Amine Transport 1 Like
Chromosome: CHR16: 77822482 -78014001
Locus: 16q23.1
Gene Diseases
The WWOX VAT1L Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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