WWOX-C15ORF41 Fusion FISH Probe
The WWOX-C15ORF41 Fusion FISH Probe is used to confirm a fusion of the WWOX and C15ORF41 genes. The fusion of the WWOX and C15ORF41 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WWOX-C15ORF41-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-RERE | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-REOR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-REGO | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-REGR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-REAQ | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-ORRE | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-OROR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-ORGO | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-ORAQ | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GORE | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GOOR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GOGO | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GOGR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GOAQ | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GRRE | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GROR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GRGO | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GRGR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-GRAQ | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-AQRE | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-AQOR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-AQGO | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-AQGR | 20 (40 μL) | 200 μL |
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| WWOX-C15ORF41-20-AQAQ | 20 (40 μL) | 200 μL |
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WWOX Gene Summary
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: WW Domain Containing Oxidoreductase
Chromosome: CHR16: 78133326 -79246564
Locus: 16q23.1-q23.2
C15orf41 Gene Summary
This gene encodes a protein with two predicted helix-turn-helix domains. Mutations in this gene were found in families with congenital dyserythropoietic anemia type Ib. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Gene Name: Chromosome 15 Open Reading Frame 41
Chromosome: CHR15: 36871811 -37102449
Locus: 15q14
Gene Diseases
The WWOX C15ORF41 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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