WWC3-SHROOM2 Fusion FISH Probe
The WWC3-SHROOM2 Fusion FISH Probe is used to confirm a fusion of the WWC3 and SHROOM2 genes. The fusion of the WWC3 and SHROOM2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WWC3-SHROOM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-RERE | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-REOR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-REGO | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-REGR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-REAQ | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-ORRE | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-OROR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-ORGO | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GORE | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GOOR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GOGO | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GOGR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GRRE | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GROR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GRGO | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GRGR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-AQRE | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-AQOR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-AQGO | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-AQGR | 20 (40 μL) | 200 μL |
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| WWC3-SHROOM2-20-AQAQ | 20 (40 μL) | 200 μL |
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SHROOM2 Gene Summary
This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Shroom Family Member 2
Chromosome: CHRX: 9754495 -9917481
Locus: Xp22.2
WWC3 Gene Summary
This gene encodes a member of the WWC family of proteins, which also includes the WWC1 (KIBRA) gene product and the WWC2 gene product. The protein encoded by this gene includes a C2 domain, which is known to mediate homodimerization in the related WWC1 gene product. [provided by RefSeq, Sep 2011]
Gene Name: WWC Family Member 3
Chromosome: CHRX: 9983794 -10112518
Locus: Xp22.2
Gene Diseases
The WWC3 SHROOM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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