WSCD1-NLRP1 Fusion FISH Probe
The WSCD1-NLRP1 Fusion FISH Probe is used to confirm a fusion of the WSCD1 and NLRP1 genes. The fusion of the WSCD1 and NLRP1 genes has been associated with Kidney Renal Clear Cell Carcinoma, and Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WSCD1-NLRP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-RERE | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-REOR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-REGO | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-REGR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-REAQ | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-ORRE | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-OROR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-ORGO | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GORE | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GOOR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GOGO | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GOGR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GRRE | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GROR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GRGO | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GRGR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-AQRE | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-AQOR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-AQGO | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-AQGR | 20 (40 μL) | 200 μL |
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| WSCD1-NLRP1-20-AQAQ | 20 (40 μL) | 200 μL |
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NLRP1 Gene Summary
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: NLR Family Pyrin Domain Containing 1
Chromosome: CHR17: 5404718 -5487832
Locus: 17p13.2
WSCD1 Gene Summary
The WSC Domain Containing 1 (WSCD1) gene is located on chr17 :5973933-6027747 at 17p13.2.
Gene Name: WSC Domain Containing 1
Chromosome: CHR17: 5973933 -6027747
Locus: 17p13.2
Gene Diseases
The WSCD1 NLRP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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