WRB-KCNJ15 Fusion FISH Probe
The WRB-KCNJ15 Fusion FISH Probe is used to confirm a fusion of the WRB and KCNJ15 genes. The fusion of the WRB and KCNJ15 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WRB-KCNJ15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-RERE | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-REOR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-REGO | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-REGR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-REAQ | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-ORRE | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-OROR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-ORGO | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-ORAQ | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GORE | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GOOR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GOGO | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GOGR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GOAQ | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GRRE | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GROR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GRGO | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GRGR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-GRAQ | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-AQRE | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-AQOR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-AQGO | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-AQGR | 20 (40 μL) | 200 μL |
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| WRB-KCNJ15-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNJ15 Gene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Name: Potassium Voltage-gated Channel Subfamily J Member 15
Chromosome: CHR21: 39628663 -39673746
Locus: 21q22.13-q22.2
WRB Gene Summary
This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4. [provided by RefSeq, Apr 2017]
Gene Name: Tryptophan Rich Basic Protein
Chromosome: CHR21: 40752212 -40769815
Locus: 21q22.2
Gene Diseases
The WRB KCNJ15 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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