WIPF2-RAMP2 Fusion FISH Probe
The WIPF2-RAMP2 Fusion FISH Probe is used to confirm a fusion of the WIPF2 and RAMP2 genes. The fusion of the WIPF2 and RAMP2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WIPF2-RAMP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-RERE | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-REOR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-REGO | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-REGR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-REAQ | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-ORRE | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-OROR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-ORGO | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GORE | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GOOR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GOGO | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GOGR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GRRE | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GROR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GRGO | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GRGR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-AQRE | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-AQOR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-AQGO | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-AQGR | 20 (40 μL) | 200 μL |
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| WIPF2-RAMP2-20-AQAQ | 20 (40 μL) | 200 μL |
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RAMP2 Gene Summary
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq, Jul 2008]
Gene Name: Receptor Activity Modifying Protein 2
Chromosome: CHR17: 40913211 -40915060
Locus: 17q21.2
WIPF2 Gene Summary
This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery. [provided by RefSeq, Jul 2008]
Gene Name: WAS/WASL Interacting Protein Family Member 2
Chromosome: CHR17: 38375573 -38438439
Locus: 17q21.2
Gene Diseases
The WIPF2 RAMP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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