WDR82-UBE4B Fusion FISH Probe
The WDR82-UBE4B Fusion FISH Probe is used to confirm a fusion of the WDR82 and UBE4B genes. The fusion of the WDR82 and UBE4B genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WDR82-UBE4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-RERE | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-REOR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-REGO | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-REGR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-REAQ | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-ORRE | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-OROR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-ORGO | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GORE | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GOOR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GOGO | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GOGR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GRRE | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GROR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GRGO | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GRGR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-AQRE | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-AQOR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-AQGO | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-AQGR | 20 (40 μL) | 200 μL |
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| WDR82-UBE4B-20-AQAQ | 20 (40 μL) | 200 μL |
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UBE4B Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitination Factor E4B
Chromosome: CHR1: 10093040 -10241296
Locus: 1p36.22
WDR82 Gene Summary
TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010]
Gene Name: WD Repeat Domain 82
Chromosome: CHR3: 52288437 -52312659
Locus: 3p21.2
Gene Diseases
The WDR82 UBE4B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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