WDR70-AGXT2 Fusion FISH Probe
The WDR70-AGXT2 Fusion FISH Probe is used to confirm a fusion of the WDR70 and AGXT2 genes. The fusion of the WDR70 and AGXT2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WDR70-AGXT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-RERE | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-REOR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-REGO | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-REGR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-REAQ | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-ORRE | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-OROR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-ORGO | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GORE | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GOOR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GOGO | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GOGR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GRRE | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GROR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GRGO | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GRGR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-AQRE | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-AQOR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-AQGO | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-AQGR | 20 (40 μL) | 200 μL |
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| WDR70-AGXT2-20-AQAQ | 20 (40 μL) | 200 μL |
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WDR70 Gene Summary
The WD Repeat Domain 70 (WDR70) gene is located on chr5 :37379411-37752774 at 5p13.2.
Gene Name: WD Repeat Domain 70
Chromosome: CHR5: 37379411 -37752774
Locus: 5p13.2
AGXT2 Gene Summary
The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Name: Alanine--glyoxylate Aminotransferase 2
Chromosome: CHR5: 34998205 -35048240
Locus: 5p13.2
Gene Diseases
The WDR70 AGXT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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