WDR62-HCST Fusion FISH Probe
The WDR62-HCST Fusion FISH Probe is used to confirm a fusion of the WDR62 and HCST genes. The fusion of the WDR62 and HCST genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WDR62-HCST-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-RERE | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-REOR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-REGO | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-REGR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-REAQ | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-ORRE | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-OROR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-ORGO | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-ORAQ | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GORE | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GOOR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GOGO | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GOGR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GOAQ | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GRRE | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GROR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GRGO | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GRGR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-GRAQ | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-AQRE | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-AQOR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-AQGO | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-AQGR | 20 (40 μL) | 200 μL |
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| WDR62-HCST-20-AQAQ | 20 (40 μL) | 200 μL |
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HCST Gene Summary
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Hematopoietic Cell Signal Transducer
Chromosome: CHR19: 36393381 -36395173
Locus: 19q13.12
WDR62 Gene Summary
This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
Gene Name: WD Repeat Domain 62
Chromosome: CHR19: 36545782 -36596012
Locus: 19q13.12
Gene Diseases
The WDR62 HCST Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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