WDR17-LTA4H Fusion FISH Probe
The WDR17-LTA4H Fusion FISH Probe is used to confirm a fusion of the WDR17 and LTA4H genes. The fusion of the WDR17 and LTA4H genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WDR17-LTA4H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-RERE | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-REOR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-REGO | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-REGR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-OROR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GORE | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GROR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| WDR17-LTA4H-20-AQAQ | 20 (40 μL) | 200 μL |
|
LTA4H Gene Summary
The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Gene Name: Leukotriene A4 Hydrolase
Chromosome: CHR12: 96394610 -96429365
Locus: 12q23.1
WDR17 Gene Summary
This gene encodes a WD repeat-containing protein. It is abundantly expressed in retina and testis, and is thought to be a candidate gene for retinal disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2009]
Gene Name: WD Repeat Domain 17
Chromosome: CHR4: 176986984 -177103979
Locus: 4q34.2
Gene Diseases
The WDR17 LTA4H Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|