WDR11-PDLIM1 Fusion FISH Probe
The WDR11-PDLIM1 Fusion FISH Probe is used to confirm a fusion of the WDR11 and PDLIM1 genes. The fusion of the WDR11 and PDLIM1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WDR11-PDLIM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-RERE | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-REOR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-REGO | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-REGR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-REAQ | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-ORRE | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-OROR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-ORGO | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GORE | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GOOR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GOGO | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GOGR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GRRE | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GROR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GRGO | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GRGR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-AQRE | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-AQOR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-AQGO | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-AQGR | 20 (40 μL) | 200 μL |
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| WDR11-PDLIM1-20-AQAQ | 20 (40 μL) | 200 μL |
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PDLIM1 Gene Summary
This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012]
Gene Name: PDZ And LIM Domain 1
Chromosome: CHR10: 96997329 -97050781
Locus: 10q23.33
WDR11 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 11
Chromosome: CHR10: 122610686 -122669038
Locus: 10q26.12
Gene Diseases
The WDR11 PDLIM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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