WASF2-TMEM222 Fusion FISH Probe
The WASF2-TMEM222 Fusion FISH Probe is used to confirm a fusion of the WASF2 and TMEM222 genes. The fusion of the WASF2 and TMEM222 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WASF2-TMEM222-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-RERE | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-REOR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-REGO | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-REGR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-REAQ | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-ORRE | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-OROR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-ORGO | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-ORAQ | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GORE | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GOOR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GOGO | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GOGR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GOAQ | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GRRE | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GROR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GRGO | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GRGR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-GRAQ | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-AQRE | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-AQOR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-AQGO | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-AQGR | 20 (40 μL) | 200 μL |
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| WASF2-TMEM222-20-AQAQ | 20 (40 μL) | 200 μL |
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WASF2 Gene Summary
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Name: WAS Protein Family Member 2
Chromosome: CHR1: 27730733 -27816678
Locus: 1p36.11
TMEM222 Gene Summary
The Transmembrane Protein 222 (TMEM222) gene is located on chr1 :27648635-27662891 at 1p36.11.
Gene Name: Transmembrane Protein 222
Chromosome: CHR1: 27648635 -27662891
Locus: 1p36.11
Gene Diseases
The WASF2 TMEM222 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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