WASF2-AHDC1 Fusion FISH Probe
The WASF2-AHDC1 Fusion FISH Probe is used to confirm a fusion of the WASF2 and AHDC1 genes. The fusion of the WASF2 and AHDC1 genes has been associated with Lung Squamous Cell Carcinoma, Lung Squamous Cell Carcinoma, Lung Squamous Cell Carcinoma, Lung Squamous Cell Carcinoma, Lung Squamous Cell Carcinoma, Lung Squamous Cell Carcinoma, Head And Neck Squamous Cell Carcinoma , Breast Invasive Carcinoma, and Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WASF2-AHDC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-RERE | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-REOR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-REGO | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-REGR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-REAQ | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-ORRE | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-OROR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-ORGO | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GORE | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GOOR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GOGO | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GOGR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GRRE | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GROR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GRGO | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GRGR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-AQRE | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-AQOR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-AQGO | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-AQGR | 20 (40 μL) | 200 μL |
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| WASF2-AHDC1-20-AQAQ | 20 (40 μL) | 200 μL |
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WASF2 Gene Summary
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Name: WAS Protein Family Member 2
Chromosome: CHR1: 27730733 -27816678
Locus: 1p36.11
AHDC1 Gene Summary
This gene encodes a protein containing two AT-hooks, which likely function in DNA binding. Mutations in this gene were found in individuals with Xia-Gibbs syndrome. [provided by RefSeq, Jun 2014]
Gene Name: AT-hook DNA Binding Motif Containing 1
Chromosome: CHR1: 27860755 -27930143
Locus: 1p36.11-p35.3
Gene Diseases
The WASF2 AHDC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Lung Squamous Cell Carcinoma |
| Lung Squamous Cell Carcinoma |
| Lung Squamous Cell Carcinoma |
| Lung Squamous Cell Carcinoma |
| Lung Squamous Cell Carcinoma |
| Head And Neck Squamous Cell Carcinoma |
| Breast Invasive Carcinoma |
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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