WARS-PPP2R3C Fusion FISH Probe
The WARS-PPP2R3C Fusion FISH Probe is used to confirm a fusion of the WARS and PPP2R3C genes. The fusion of the WARS and PPP2R3C genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WARS-PPP2R3C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-RERE | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-REOR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-REGO | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-REGR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-OROR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GORE | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GROR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| WARS-PPP2R3C-20-AQAQ | 20 (40 μL) | 200 μL |
|
WARS Gene Summary
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tryptophanyl-tRNA Synthetase
Chromosome: CHR14: 100800124 -100842680
Locus: 14q32.2
PPP2R3C Gene Summary
This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Name: Protein Phosphatase 2 Regulatory Subunit B''gamma
Chromosome: CHR14: 35554677 -35591519
Locus: 14q13.2
Gene Diseases
The WARS PPP2R3C Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|