WAC-RDX Fusion FISH Probe
The WAC-RDX Fusion FISH Probe is used to confirm a fusion of the WAC and RDX genes. The fusion of the WAC and RDX genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WAC-RDX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-RERE | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-REOR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-REGO | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-REGR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-REAQ | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-ORRE | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-OROR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-ORGO | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-ORAQ | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GORE | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GOOR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GOGO | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GOGR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GOAQ | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GRRE | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GROR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GRGO | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GRGR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-GRAQ | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-AQRE | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-AQOR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-AQGO | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-AQGR | 20 (40 μL) | 200 μL |
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| WAC-RDX-20-AQAQ | 20 (40 μL) | 200 μL |
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RDX Gene Summary
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: Radixin
Chromosome: CHR11: 110100165 -110167437
Locus: 11q22.3
WAC Gene Summary
The protein encoded by this gene contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short linear peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however, its exact function is not known. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Gene Name: WW Domain Containing Adaptor With Coiled-coil
Chromosome: CHR10: 28821421 -28912041
Locus: 10p12.1-p11.2
Gene Diseases
The WAC RDX Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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