VTCN1-NUP88 Fusion FISH Probe
The VTCN1-NUP88 Fusion FISH Probe is used to confirm a fusion of the VTCN1 and NUP88 genes. The fusion of the VTCN1 and NUP88 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VTCN1-NUP88-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-RERE | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-REOR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-REGO | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-REGR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-REAQ | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-ORRE | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-OROR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-ORGO | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-ORAQ | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GORE | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GOOR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GOGO | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GOGR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GOAQ | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GRRE | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GROR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GRGO | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GRGR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-GRAQ | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-AQRE | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-AQOR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-AQGO | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-AQGR | 20 (40 μL) | 200 μL |
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| VTCN1-NUP88-20-AQAQ | 20 (40 μL) | 200 μL |
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NUP88 Gene Summary
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Gene Name: Nucleoporin 88
Chromosome: CHR17: 5289345 -5323059
Locus: 17p13.2
VTCN1 Gene Summary
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: V-set Domain Containing T-cell Activation Inhibitor 1
Chromosome: CHR1: 117686208 -117753549
Locus: 1p13.1-p12
Gene Diseases
The VTCN1 NUP88 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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