VPS8-NPHP3 Fusion FISH Probe
The VPS8-NPHP3 Fusion FISH Probe is used to confirm a fusion of the VPS8 and NPHP3 genes. The fusion of the VPS8 and NPHP3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VPS8-NPHP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-RERE | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-REOR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-REGO | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-REGR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-REAQ | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-ORRE | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-OROR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-ORGO | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GORE | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GOOR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GOGO | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GOGR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GRRE | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GROR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GRGO | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GRGR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-AQRE | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-AQOR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-AQGO | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-AQGR | 20 (40 μL) | 200 μL |
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| VPS8-NPHP3-20-AQAQ | 20 (40 μL) | 200 μL |
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VPS8 Gene Summary
The VPS8, CORVET Complex Subunit (VPS8) gene is located on chr3 :184529930-184770402 at 3q27.2.
Gene Name: VPS8, CORVET Complex Subunit
Chromosome: CHR3: 184529930 -184770402
Locus: 3q27.2
NPHP3 Gene Summary
This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene. [provided by RefSeq, Feb 2011]
Gene Name: Nephrocystin 3
Chromosome: CHR3: 132399452 -132441303
Locus: 3q22.1
Gene Diseases
The VPS8 NPHP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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