VPS8-EPHB3 Fusion FISH Probe
The VPS8-EPHB3 Fusion FISH Probe is used to confirm a fusion of the VPS8 and EPHB3 genes. The fusion of the VPS8 and EPHB3 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VPS8-EPHB3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-RERE | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-REOR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-REGO | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-REGR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-REAQ | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-ORRE | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-OROR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-ORGO | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-ORAQ | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GORE | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GOOR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GOGO | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GOGR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GOAQ | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GRRE | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GROR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GRGO | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GRGR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-GRAQ | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-AQRE | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-AQOR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-AQGO | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-AQGR | 20 (40 μL) | 200 μL |
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| VPS8-EPHB3-20-AQAQ | 20 (40 μL) | 200 μL |
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EPHB3 Gene Summary
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010]
Gene Name: EPH Receptor B3
Chromosome: CHR3: 184279586 -184300196
Locus: 3q27.1
VPS8 Gene Summary
The VPS8, CORVET Complex Subunit (VPS8) gene is located on chr3 :184529930-184770402 at 3q27.2.
Gene Name: VPS8, CORVET Complex Subunit
Chromosome: CHR3: 184529930 -184770402
Locus: 3q27.2
Gene Diseases
The VPS8 EPHB3 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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