VPS4B-SLC22A15 Fusion FISH Probe
The VPS4B-SLC22A15 Fusion FISH Probe is used to confirm a fusion of the VPS4B and SLC22A15 genes. The fusion of the VPS4B and SLC22A15 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VPS4B-SLC22A15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-RERE | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-REOR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-REGO | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-REGR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-REAQ | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-ORRE | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-OROR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-ORGO | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-ORAQ | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GORE | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GOOR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GOGO | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GOGR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GOAQ | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GRRE | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GROR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GRGO | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GRGR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-GRAQ | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-AQRE | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-AQOR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-AQGO | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-AQGR | 20 (40 μL) | 200 μL |
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| VPS4B-SLC22A15-20-AQAQ | 20 (40 μL) | 200 μL |
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VPS4B Gene Summary
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq, Jul 2008]
Gene Name: Vacuolar Protein Sorting 4 Homolog B
Chromosome: CHR18: 61056424 -61089752
Locus: 18q21.33
SLC22A15 Gene Summary
Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds, including pharmaceuticals, toxins, hormones, neurotransmitters, and cellular metabolites. These transporters are also referred to as amphiphilic solute facilitators (ASFs).[supplied by OMIM, Apr 2004]
Gene Name: Solute Carrier Family 22 Member 15
Chromosome: CHR1: 116519118 -116612675
Locus: 1p13.1
Gene Diseases
The VPS4B SLC22A15 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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