VPS41-NPSR1 Fusion FISH Probe
The VPS41-NPSR1 Fusion FISH Probe is used to confirm a fusion of the VPS41 and NPSR1 genes. The fusion of the VPS41 and NPSR1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VPS41-NPSR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-RERE | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-REOR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-REGO | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-REGR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-REAQ | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-ORRE | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-OROR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-ORGO | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GORE | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GOOR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GOGO | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GOGR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GRRE | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GROR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GRGO | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GRGR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-AQRE | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-AQOR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-AQGO | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-AQGR | 20 (40 μL) | 200 μL |
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| VPS41-NPSR1-20-AQAQ | 20 (40 μL) | 200 μL |
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VPS41 Gene Summary
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]
Gene Name: VPS41, HOPS Complex Subunit
Chromosome: CHR7: 38763542 -38948800
Locus: 7p14.1
NPSR1 Gene Summary
This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: Neuropeptide S Receptor 1
Chromosome: CHR7: 34697896 -34917944
Locus: 7p14.3
Gene Diseases
The VPS41 NPSR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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