VPS41-AES Fusion FISH Probe
The VPS41-AES Fusion FISH Probe is used to confirm a fusion of the VPS41 and AES genes. The fusion of the VPS41 and AES genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VPS41-AES-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-RERE | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-REOR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-REGO | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-REGR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-REAQ | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-ORRE | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-OROR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-ORGO | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-ORAQ | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GORE | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GOOR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GOGO | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GOGR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GOAQ | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GRRE | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GROR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GRGO | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GRGR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-GRAQ | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-AQRE | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-AQOR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-AQGO | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-AQGR | 20 (40 μL) | 200 μL |
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| VPS41-AES-20-AQAQ | 20 (40 μL) | 200 μL |
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AES Gene Summary
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Amino-terminal Enhancer Of Split
Chromosome: CHR19: 3052907 -3062964
Locus: 19p13.3
VPS41 Gene Summary
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]
Gene Name: VPS41, HOPS Complex Subunit
Chromosome: CHR7: 38763542 -38948800
Locus: 7p14.1
Gene Diseases
The VPS41 AES Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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