VPS13B-STAU2 Fusion FISH Probe
The VPS13B-STAU2 Fusion FISH Probe is used to confirm a fusion of the VPS13B and STAU2 genes. The fusion of the VPS13B and STAU2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VPS13B-STAU2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-RERE | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-REOR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-REGO | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-REGR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-REAQ | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-ORRE | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-OROR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-ORGO | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-ORAQ | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GORE | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GOOR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GOGO | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GOGR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GOAQ | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GRRE | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GROR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GRGO | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GRGR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-GRAQ | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-AQRE | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-AQOR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-AQGO | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-AQGR | 20 (40 μL) | 200 μL |
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| VPS13B-STAU2-20-AQAQ | 20 (40 μL) | 200 μL |
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STAU2 Gene Summary
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Name: Staufen Double-stranded RNA Binding Protein 2
Chromosome: CHR8: 74332603 -74659162
Locus: 8q21.11
VPS13B Gene Summary
This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Vacuolar Protein Sorting 13 Homolog B
Chromosome: CHR8: 100025493 -100889808
Locus: 8q22.2
Gene Diseases
The VPS13B STAU2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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