VPS13B-AKAP7 Fusion FISH Probe
The VPS13B-AKAP7 Fusion FISH Probe is used to confirm a fusion of the VPS13B and AKAP7 genes. The fusion of the VPS13B and AKAP7 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VPS13B-AKAP7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-RERE | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-REOR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-REGO | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-REGR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-REAQ | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-ORRE | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-OROR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-ORGO | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-ORAQ | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GORE | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GOOR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GOGO | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GOGR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GOAQ | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GRRE | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GROR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GRGO | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GRGR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-GRAQ | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-AQRE | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-AQOR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-AQGO | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-AQGR | 20 (40 μL) | 200 μL |
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| VPS13B-AKAP7-20-AQAQ | 20 (40 μL) | 200 μL |
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AKAP7 Gene Summary
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011]
Gene Name: A-kinase Anchoring Protein 7
Chromosome: CHR6: 131456825 -131604675
Locus: 6q23.2
VPS13B Gene Summary
This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Vacuolar Protein Sorting 13 Homolog B
Chromosome: CHR8: 100025493 -100889808
Locus: 8q22.2
Gene Diseases
The VPS13B AKAP7 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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