VIM-SIAE Fusion FISH Probe
The VIM-SIAE Fusion FISH Probe is used to confirm a fusion of the VIM and SIAE genes. The fusion of the VIM and SIAE genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VIM-SIAE-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-RERE | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-REOR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-REGO | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-REGR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-REAQ | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-ORRE | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-OROR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-ORGO | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-ORAQ | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GORE | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GOOR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GOGO | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GOGR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GOAQ | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GRRE | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GROR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GRGO | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GRGR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-GRAQ | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-AQRE | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-AQOR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-AQGO | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-AQGR | 20 (40 μL) | 200 μL |
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| VIM-SIAE-20-AQAQ | 20 (40 μL) | 200 μL |
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VIM Gene Summary
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
Gene Name: Vimentin
Chromosome: CHR10: 17270257 -17279592
Locus: 10p13
SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
Gene Diseases
The VIM SIAE Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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