VIM-SGK3 Fusion FISH Probe
The VIM-SGK3 Fusion FISH Probe is used to confirm a fusion of the VIM and SGK3 genes. The fusion of the VIM and SGK3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VIM-SGK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-RERE | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-REOR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-REGO | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-REGR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-REAQ | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-ORRE | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-OROR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-ORGO | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GORE | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GOOR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GOGO | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GOGR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GRRE | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GROR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GRGO | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GRGR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-AQRE | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-AQOR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-AQGO | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-AQGR | 20 (40 μL) | 200 μL |
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| VIM-SGK3-20-AQAQ | 20 (40 μL) | 200 μL |
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VIM Gene Summary
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
Gene Name: Vimentin
Chromosome: CHR10: 17270257 -17279592
Locus: 10p13
SGK3 Gene Summary
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Serum/glucocorticoid Regulated Kinase Family Member 3
Chromosome: CHR8: 67624652 -67774257
Locus: 8q13.1
Gene Diseases
The VIM SGK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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