VIM-PEX1 Fusion FISH Probe
The VIM-PEX1 Fusion FISH Probe is used to confirm a fusion of the VIM and PEX1 genes. The fusion of the VIM and PEX1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VIM-PEX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-RERE | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-REOR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-REGO | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-REGR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-REAQ | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-ORRE | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-OROR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-ORGO | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GORE | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GOOR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GOGO | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GOGR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GRRE | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GROR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GRGO | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GRGR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-AQRE | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-AQOR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-AQGO | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-AQGR | 20 (40 μL) | 200 μL |
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| VIM-PEX1-20-AQAQ | 20 (40 μL) | 200 μL |
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PEX1 Gene Summary
This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Peroxisomal Biogenesis Factor 1
Chromosome: CHR7: 92116336 -92157845
Locus: 7q21.2
VIM Gene Summary
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
Gene Name: Vimentin
Chromosome: CHR10: 17270257 -17279592
Locus: 10p13
Gene Diseases
The VIM PEX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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