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VGF-SIAE Fusion FISH Probe

The VGF-SIAE Fusion FISH Probe is used to confirm a fusion of the VGF and SIAE genes. The fusion of the VGF and SIAE genes has been associated with Skin Cutaneous Melanoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
VGF-SIAE-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
VGF-SIAE-20-RERE 20 (40 μL) 200 μL
VGF-SIAE-20-REOR 20 (40 μL) 200 μL
VGF-SIAE-20-REGO 20 (40 μL) 200 μL
VGF-SIAE-20-REGR 20 (40 μL) 200 μL
VGF-SIAE-20-REAQ 20 (40 μL) 200 μL
VGF-SIAE-20-ORRE 20 (40 μL) 200 μL
VGF-SIAE-20-OROR 20 (40 μL) 200 μL
VGF-SIAE-20-ORGO 20 (40 μL) 200 μL
VGF-SIAE-20-ORAQ 20 (40 μL) 200 μL
VGF-SIAE-20-GORE 20 (40 μL) 200 μL
VGF-SIAE-20-GOOR 20 (40 μL) 200 μL
VGF-SIAE-20-GOGO 20 (40 μL) 200 μL
VGF-SIAE-20-GOGR 20 (40 μL) 200 μL
VGF-SIAE-20-GOAQ 20 (40 μL) 200 μL
VGF-SIAE-20-GRRE 20 (40 μL) 200 μL
VGF-SIAE-20-GROR 20 (40 μL) 200 μL
VGF-SIAE-20-GRGO 20 (40 μL) 200 μL
VGF-SIAE-20-GRGR 20 (40 μL) 200 μL
VGF-SIAE-20-GRAQ 20 (40 μL) 200 μL
VGF-SIAE-20-AQRE 20 (40 μL) 200 μL
VGF-SIAE-20-AQOR 20 (40 μL) 200 μL
VGF-SIAE-20-AQGO 20 (40 μL) 200 μL
VGF-SIAE-20-AQGR 20 (40 μL) 200 μL
VGF-SIAE-20-AQAQ 20 (40 μL) 200 μL

VGF Gene Summary

This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008]

Gene Name: VGF Nerve Growth Factor Inducible

Chromosome: CHR7: 100805789 -100808852

Locus: 7q22.1

SIAE Gene Summary

This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]

Gene Name: Sialic Acid Acetylesterase

Chromosome: CHR11: 124505684 -124546199

Locus: 11q24.2

Gene Diseases

The VGF SIAE Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.