VCL-SFTPD Fusion FISH Probe
The VCL-SFTPD Fusion FISH Probe is used to confirm a fusion of the VCL and SFTPD genes. The fusion of the VCL and SFTPD genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VCL-SFTPD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-RERE | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-REOR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-REGO | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-REGR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-REAQ | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-ORRE | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-OROR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-ORGO | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-ORAQ | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GORE | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GOOR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GOGO | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GOGR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GOAQ | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GRRE | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GROR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GRGO | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GRGR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-GRAQ | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-AQRE | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-AQOR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-AQGO | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-AQGR | 20 (40 μL) | 200 μL |
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| VCL-SFTPD-20-AQAQ | 20 (40 μL) | 200 μL |
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SFTPD Gene Summary
The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]
Gene Name: Surfactant Protein D
Chromosome: CHR10: 81697495 -81708861
Locus: 10q22.3
VCL Gene Summary
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Vinculin
Chromosome: CHR10: 75757871 -75879914
Locus: 10q22.2
Gene Diseases
The VCL SFTPD Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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