VBP1-GABRA3 Fusion FISH Probe
The VBP1-GABRA3 Fusion FISH Probe is used to confirm a fusion of the VBP1 and GABRA3 genes. The fusion of the VBP1 and GABRA3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VBP1-GABRA3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-RERE | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-REOR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-REGO | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-REGR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-REAQ | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-ORRE | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-OROR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-ORGO | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-ORAQ | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GORE | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GOOR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GOGO | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GOGR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GOAQ | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GRRE | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GROR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GRGO | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GRGR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-GRAQ | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-AQRE | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-AQOR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-AQGO | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-AQGR | 20 (40 μL) | 200 μL |
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| VBP1-GABRA3-20-AQAQ | 20 (40 μL) | 200 μL |
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GABRA3 Gene Summary
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Gamma-aminobutyric Acid Type A Receptor Alpha3 Subunit
Chromosome: CHRX: 151335633 -151619831
Locus: Xq28
VBP1 Gene Summary
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]
Gene Name: VHL Binding Protein 1
Chromosome: CHRX: 154444700 -154468098
Locus: Xq28
Gene Diseases
The VBP1 GABRA3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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