VAV3-RGL1 Fusion FISH Probe
The VAV3-RGL1 Fusion FISH Probe is used to confirm a fusion of the VAV3 and RGL1 genes. The fusion of the VAV3 and RGL1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VAV3-RGL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-RERE | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-REOR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-REGO | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-REGR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-REAQ | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-ORRE | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-OROR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-ORGO | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GORE | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GOOR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GOGO | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GOGR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GRRE | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GROR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GRGO | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GRGR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-AQRE | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-AQOR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-AQGO | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-AQGR | 20 (40 μL) | 200 μL |
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| VAV3-RGL1-20-AQAQ | 20 (40 μL) | 200 μL |
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VAV3 Gene Summary
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Vav Guanine Nucleotide Exchange Factor 3
Chromosome: CHR1: 108113781 -108507545
Locus: 1p13.3
RGL1 Gene Summary
The Ral Guanine Nucleotide Dissociation Stimulator Like 1 (RGL1) gene is located on chr1 :183605207-183897666 at 1q25.3.
Gene Name: Ral Guanine Nucleotide Dissociation Stimulator Like 1
Chromosome: CHR1: 183605207 -183897666
Locus: 1q25.3
Gene Diseases
The VAV3 RGL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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