VAV2-BRD3 Fusion FISH Probe
The VAV2-BRD3 Fusion FISH Probe is used to confirm a fusion of the VAV2 and BRD3 genes. The fusion of the VAV2 and BRD3 genes has been associated with Liver Hepatocellular Carcinoma, Head And Neck Squamous Cell Carcinoma , Pheochromocytoma And Paraganglioma, and Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VAV2-BRD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-RERE | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-REOR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-REGO | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-REGR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-REAQ | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-ORRE | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-OROR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-ORGO | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GORE | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GOOR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GOGO | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GOGR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GRRE | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GROR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GRGO | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GRGR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-AQRE | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-AQOR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-AQGO | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-AQGR | 20 (40 μL) | 200 μL |
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| VAV2-BRD3-20-AQAQ | 20 (40 μL) | 200 μL |
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VAV2 Gene Summary
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Vav Guanine Nucleotide Exchange Factor 2
Chromosome: CHR9: 136627015 -136857446
Locus: 9q34.2
BRD3 Gene Summary
This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008]
Gene Name: Bromodomain Containing 3
Chromosome: CHR9: 136895445 -136933141
Locus: 9q34.2
Gene Diseases
The VAV2 BRD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
| Head And Neck Squamous Cell Carcinoma |
| Pheochromocytoma And Paraganglioma |
| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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