VAV1-C1ORF198 Fusion FISH Probe
The VAV1-C1ORF198 Fusion FISH Probe is used to confirm a fusion of the VAV1 and C1ORF198 genes. The fusion of the VAV1 and C1ORF198 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VAV1-C1ORF198-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-RERE | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-REOR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-REGO | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-REGR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-REAQ | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-ORRE | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-OROR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-ORGO | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-ORAQ | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GORE | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GOOR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GOGO | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GOGR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GOAQ | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GRRE | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GROR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GRGO | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GRGR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-GRAQ | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-AQRE | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-AQOR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-AQGO | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-AQGR | 20 (40 μL) | 200 μL |
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| VAV1-C1ORF198-20-AQAQ | 20 (40 μL) | 200 μL |
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VAV1 Gene Summary
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
Gene Name: Vav Guanine Nucleotide Exchange Factor 1
Chromosome: CHR19: 6772721 -6857371
Locus: 19p13.3
C1orf198 Gene Summary
The Chromosome 1 Open Reading Frame 198 (C1orf198) gene is located on chr1 :230972864-231005335 at 1q42.2.
Gene Name: Chromosome 1 Open Reading Frame 198
Chromosome: CHR1: 230972864 -231005335
Locus: 1q42.2
Gene Diseases
The VAV1 C1ORF198 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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