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VAPB-PKIA Fusion FISH Probe

The VAPB-PKIA Fusion FISH Probe is used to confirm a fusion of the VAPB and PKIA genes. The fusion of the VAPB and PKIA genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
VAPB-PKIA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
VAPB-PKIA-20-RERE 20 (40 μL) 200 μL
VAPB-PKIA-20-REOR 20 (40 μL) 200 μL
VAPB-PKIA-20-REGO 20 (40 μL) 200 μL
VAPB-PKIA-20-REGR 20 (40 μL) 200 μL
VAPB-PKIA-20-REAQ 20 (40 μL) 200 μL
VAPB-PKIA-20-ORRE 20 (40 μL) 200 μL
VAPB-PKIA-20-OROR 20 (40 μL) 200 μL
VAPB-PKIA-20-ORGO 20 (40 μL) 200 μL
VAPB-PKIA-20-ORAQ 20 (40 μL) 200 μL
VAPB-PKIA-20-GORE 20 (40 μL) 200 μL
VAPB-PKIA-20-GOOR 20 (40 μL) 200 μL
VAPB-PKIA-20-GOGO 20 (40 μL) 200 μL
VAPB-PKIA-20-GOGR 20 (40 μL) 200 μL
VAPB-PKIA-20-GOAQ 20 (40 μL) 200 μL
VAPB-PKIA-20-GRRE 20 (40 μL) 200 μL
VAPB-PKIA-20-GROR 20 (40 μL) 200 μL
VAPB-PKIA-20-GRGO 20 (40 μL) 200 μL
VAPB-PKIA-20-GRGR 20 (40 μL) 200 μL
VAPB-PKIA-20-GRAQ 20 (40 μL) 200 μL
VAPB-PKIA-20-AQRE 20 (40 μL) 200 μL
VAPB-PKIA-20-AQOR 20 (40 μL) 200 μL
VAPB-PKIA-20-AQGO 20 (40 μL) 200 μL
VAPB-PKIA-20-AQGR 20 (40 μL) 200 μL
VAPB-PKIA-20-AQAQ 20 (40 μL) 200 μL

PKIA Gene Summary

The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Gene Name: CAMP-dependent Protein Kinase Inhibitor Alpha

Chromosome: CHR8: 79428335 -79517502

Locus: 8q21.13

VAPB Gene Summary

The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking. [provided by RefSeq, Jul 2008]

Gene Name: VAMP Associated Protein B And C

Chromosome: CHR20: 56964174 -57026156

Locus: 20q13.32

Gene Diseases

The VAPB PKIA Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.