VAC14-HYDIN Fusion FISH Probe
The VAC14-HYDIN Fusion FISH Probe is used to confirm a fusion of the VAC14 and HYDIN genes. The fusion of the VAC14 and HYDIN genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VAC14-HYDIN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-RERE | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-REOR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-REGO | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-REGR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-REAQ | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-ORRE | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-OROR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-ORGO | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-ORAQ | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GORE | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GOOR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GOGO | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GOGR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GOAQ | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GRRE | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GROR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GRGO | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GRGR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-GRAQ | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-AQRE | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-AQOR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-AQGO | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-AQGR | 20 (40 μL) | 200 μL |
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| VAC14-HYDIN-20-AQAQ | 20 (40 μL) | 200 μL |
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HYDIN Gene Summary
This gene encodes a protein that may be involved in cilia motility. Mutations in this gene cause of autosomal recessive primary ciliary dyskinesia-5, a disorder characterized by the accumulation of cerebrospinal fluid within the ventricles of the brain. A duplicate copy of this gene has been found in humans on chromosome 1. [provided by RefSeq, Jan 2013]
Gene Name: HYDIN, Axonemal Central Pair Apparatus Protein
Chromosome: CHR16: 70841288 -71264569
Locus: 16q22.2
VAC14 Gene Summary
This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities. [provided by RefSeq, May 2017]
Gene Name: Vac14, PIKFYVE Complex Component
Chromosome: CHR16: 70721341 -70835061
Locus: 16q22.1-q22.2
Gene Diseases
The VAC14 HYDIN Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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