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UTRN-LAMB4 Fusion FISH Probe

The UTRN-LAMB4 Fusion FISH Probe is used to confirm a fusion of the UTRN and LAMB4 genes. The fusion of the UTRN and LAMB4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
UTRN-LAMB4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
UTRN-LAMB4-20-RERE 20 (40 μL) 200 μL
UTRN-LAMB4-20-REOR 20 (40 μL) 200 μL
UTRN-LAMB4-20-REGO 20 (40 μL) 200 μL
UTRN-LAMB4-20-REGR 20 (40 μL) 200 μL
UTRN-LAMB4-20-REAQ 20 (40 μL) 200 μL
UTRN-LAMB4-20-ORRE 20 (40 μL) 200 μL
UTRN-LAMB4-20-OROR 20 (40 μL) 200 μL
UTRN-LAMB4-20-ORGO 20 (40 μL) 200 μL
UTRN-LAMB4-20-ORAQ 20 (40 μL) 200 μL
UTRN-LAMB4-20-GORE 20 (40 μL) 200 μL
UTRN-LAMB4-20-GOOR 20 (40 μL) 200 μL
UTRN-LAMB4-20-GOGO 20 (40 μL) 200 μL
UTRN-LAMB4-20-GOGR 20 (40 μL) 200 μL
UTRN-LAMB4-20-GOAQ 20 (40 μL) 200 μL
UTRN-LAMB4-20-GRRE 20 (40 μL) 200 μL
UTRN-LAMB4-20-GROR 20 (40 μL) 200 μL
UTRN-LAMB4-20-GRGO 20 (40 μL) 200 μL
UTRN-LAMB4-20-GRGR 20 (40 μL) 200 μL
UTRN-LAMB4-20-GRAQ 20 (40 μL) 200 μL
UTRN-LAMB4-20-AQRE 20 (40 μL) 200 μL
UTRN-LAMB4-20-AQOR 20 (40 μL) 200 μL
UTRN-LAMB4-20-AQGO 20 (40 μL) 200 μL
UTRN-LAMB4-20-AQGR 20 (40 μL) 200 μL
UTRN-LAMB4-20-AQAQ 20 (40 μL) 200 μL

UTRN Gene Summary

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

Gene Name: Utrophin

Chromosome: CHR6: 144612872 -145174170

Locus: 6q24.2

LAMB4 Gene Summary

The Laminin Subunit Beta 4 (LAMB4) gene is located on chr7 :107663995-107770801 at 7q31.1.

Gene Name: Laminin Subunit Beta 4

Chromosome: CHR7: 107663995 -107770801

Locus: 7q31.1

Gene Diseases

The UTRN LAMB4 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.