UTRN-ECT2L Fusion FISH Probe
The UTRN-ECT2L Fusion FISH Probe is used to confirm a fusion of the UTRN and ECT2L genes. The fusion of the UTRN and ECT2L genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UTRN-ECT2L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-RERE | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-REOR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-REGO | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-REGR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-REAQ | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-ORRE | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-OROR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-ORGO | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-ORAQ | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GORE | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GOOR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GOGO | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GOGR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GOAQ | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GRRE | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GROR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GRGO | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GRGR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-GRAQ | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-AQRE | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-AQOR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-AQGO | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-AQGR | 20 (40 μL) | 200 μL |
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| UTRN-ECT2L-20-AQAQ | 20 (40 μL) | 200 μL |
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UTRN Gene Summary
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Name: Utrophin
Chromosome: CHR6: 144612872 -145174170
Locus: 6q24.2
ECT2L Gene Summary
The Epithelial Cell Transforming 2 Like (ECT2L) gene is located on chr6 :139117247-139225207 at 6q24.1.
Gene Name: Epithelial Cell Transforming 2 Like
Chromosome: CHR6: 139117247 -139225207
Locus: 6q24.1
Gene Diseases
The UTRN ECT2L Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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