USPL1-RB1 Fusion FISH Probe
The USPL1-RB1 Fusion FISH Probe is used to confirm a fusion of the USPL1 and RB1 genes. The fusion of the USPL1 and RB1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USPL1-RB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-RERE | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-REOR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-REGO | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-REGR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-REAQ | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-ORRE | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-OROR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-ORGO | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GORE | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GOOR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GOGO | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GOGR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GRRE | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GROR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GRGO | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GRGR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-AQRE | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-AQOR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-AQGO | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-AQGR | 20 (40 μL) | 200 μL |
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| USPL1-RB1-20-AQAQ | 20 (40 μL) | 200 μL |
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RB1 Gene Summary
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Gene Name: RB Transcriptional Corepressor 1
Chromosome: CHR13: 48877882 -49056026
Locus: 13q14.2
USPL1 Gene Summary
The Ubiquitin Specific Peptidase Like 1 (USPL1) gene is located on chr13 :31191829-31233686 at 13q12.3.
Gene Name: Ubiquitin Specific Peptidase Like 1
Chromosome: CHR13: 31191829 -31233686
Locus: 13q12.3
Gene Diseases
The USPL1 RB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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